As I mentioned in my last blog post, when I visited the doctor last week I was given a prescription for Orlistat. Here’s what happened next. Please note that this gets quite detailed and scatological in places, so don’t read if you’re easily squicked!
The skinny on the skinny pill
Orlistat, as most of you probably already know, is the generic name for Xenical, which is also sold under the brand name Alli in the UK. It’s the only medicine prescribed by the NHS specifically for weight loss. (I’d like at this point to mention that the NHS is incredibly awesome, and that even if I paid for my prescriptions, I would only have had to pay £7.40 for medicine which would have cost over £40 to buy over the counter. That’s pretty amazing.) Used properly, it can increase the rate of weight loss by 50% – i.e. if you’re losing 2lb a week through diet and exercise, adding in Orlistat will mean you lose 3lb.
Unlike earlier diet pills which were a combination of a stimulant and an appetite suppressant (generally amphetamine-based – basically medical speed), Orlistat works by preventing your body from absorbing some of the fat from the food you eat. You take it after every meal containing fat, up to three times a day. You have to be careful not to take other medications at the same time, as it can prevent them being absorbed properly, and you’re advised to take a vitamin supplement so you don’t miss out on important fat-soluble nutrients.
And here’s where it gets a bit gross. Because all that fat that your gut can no longer absorb has to go somewhere. And there’s only one place it can go – out. Before I started taking Orlistat I’d read plenty of horror stories about people suffering stomach cramps, diarrhoea and even (eww) oily anal leakage as their bodies struggled to eject the excess fat. I was pretty confident though – if I eat a low fat diet, there won’t be much to get rid of, so I shouldn’t get any of those symptoms. My doctor was similarly reassuring, and said that if I knew I was going to eat a more fatty meal than usual (e.g. going out for dinner) and didn’t want to risk side-effects, I should simply not take the pills that day. It seemed to make sense.
You’ve been Tangoed
I started taking the pills on the Tuesday lunchtime. I was eating pretty healthily – carrot sticks, hummus and fruit for lunches, and I’d made a big pan of Bolognese sauce to be had with baked potatoes in the evenings. I hadn’t worried too much about the fat content – it seemed fine though, and I skimmed off most of the visible fat. And sure enough, everything seemed fine – no side effects to speak of. I actually worried whether it was working or not!
Then… day four. I began to feel slightly uncomfortable, and when I went to the toilet I passed an oily orange substance. This, I knew, was the dreaded Orange Oil, which is talked about a lot on Xenical/Alli forums. Looked like my body had been saving it all up and I was now paying the price. And when I say orange, by the way, I really do mean orange – it looked like the stuff you get on the top of a dodgy vindaloo. Not offensive smelling or anything though, just bright!
OK, I thought, I clearly need to keep a tighter handle on what I’m eating. I will make sure I don’t eat much fat at all today, and it’ll settle down. The next day was Saturday and I was going up to Derbyshire to visit some friends who were throwing a party, and I knew I wouldn’t be able to keep the usual control over what I ate when I was travelling or grazing a buffet table. But, as my doctor had explained, I could simply not take the pills that day and there would be no problem. Right?
Wrong. Even though I hadn’t taken any Orlistat in 24 hours, it was obviously still in my system, and I spent most of the party nipping hurriedly to the loo and feeling quite anxious about the Orange Oil. It did rather dampen my spirits and I may not have been the life and soul of the party as I’d intended to be!
Keep taking the tablets?
I didn’t take Orlistat again for the rest of the weekend, and started taking it again on Monday of the following week. The pattern’s been very similar – no side-effects at all for the first few days, and then the oily stuff again. As side-effects go it’s not the end of the world – I’m not getting cramps or ‘the runs’, but it is embarrassing and not a little unpleasant. And feeling anxious about it is putting me off doing too much exercise in case of accidents, which might be rather self-defeating when it comes to maintaining weight loss. And let’s not talk about the crimp it might put in my sex life.
I’m still in two minds whether to carry on with it. Most reports seem to say that the side effects will get less severe after a few weeks, though how much of that is the patients simply getting too paranoid to eat any fat at all, I’m not sure. I’ll probably stick with it for another week or so, and if I feel that it doesn’t suit my lifestyle, I’ll stop taking it and let my GP know.